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20400 Observation Dr 4,197 - 42,796 SF of Space Available in Germantown, MD 20876

HIGHLIGHTS

  • Leading the way with design innovation and next-gen lab, Observation Labs offers turnkey lab/biotech space and customizable opportunities.
  • Phase 1 only has two turnkey spec suites remaining at 5,648 SF and 3,847 SF, with Phase 2 providing build-to-suit space.
  • Strategically located in the Germantown life science cluster along the Interstate 270 corridor, known as DNA Alley.
  • Expansive options for tenants looking for newly constructed spec suites or shell-ready lab space ranging from 3,600 SF to 68,000 SF.
  • Shared life science amenity room with biotech equipment including an autoclave, a glassware washer, a deionized water system, and a flake ice machine.
  • Nearby amenities include shopping centers, retailers, dining options, and entertainment.

ALL AVAILABLE SPACES(7)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 100
  • 7,028 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Direct, dedicated suite entrance with awning signage available. Newly enhanced HVAC supports specialized laboratory operations and equipment. Layout and access ideal for a surgery center.

  • Fully Built-Out as Standard Office
  • Fits 18 - 57 People
  • Mostly Open Floor Plan Layout
  • 1st Floor, Ste 120
  • 7,804 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Shell Space
  • Now

In shell condition with newly enhanced HVAC to support specialized laboratory operations, equipment, and plumbing.

  • Can be combined with additional space(s) for up to 13,960 SF of adjacent space
  • 1st Floor, Ste 130
  • 6,156 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Shell Space
  • Now

In shell condition with newly enhanced HVAC to support specialized laboratory operations, equipment, and plumbing.

  • Can be combined with additional space(s) for up to 13,960 SF of adjacent space
  • 1st Floor, Ste 140
  • 5,654 SF
  • Negotiable
  • $35.50 /SF/YR $2.96 /SF/MO $382.12 /m²/YR $31.84 /m²/MO $16,726 /MO $200,717 /YR
  • Office
  • Spec Suite
  • Now

Newly delivered spec lab suite with high-end finishes, offering a modern lab/office build-out and immediate occupancy.

  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Fits 20 - 63 People
  • 2nd Floor, Ste 200
  • 7,538 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Direct, dedicated suite entrance with awning signage available.

  • Fully Built-Out as Standard Office
  • Fits 19 - 61 People
  • Mostly Open Floor Plan Layout
  • 2nd Floor, Ste 230
  • 4,197 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Shell Space
  • Now

In shell condition.

  • 2nd Floor, Ste 260
  • 4,419 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

In shell condition.

  • Fully Built-Out as Standard Office
  • Fits 12 - 36 People
  • Mostly Open Floor Plan Layout
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 100 7,028 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
1st Floor, Ste 120 7,804 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Office/Medical Shell Space Now
1st Floor, Ste 130 6,156 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Office/Medical Shell Space Now
1st Floor, Ste 140 5,654 SF Negotiable $35.50 /SF/YR $2.96 /SF/MO $382.12 /m²/YR $31.84 /m²/MO $16,726 /MO $200,717 /YR Office Spec Suite Now
2nd Floor, Ste 200 7,538 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
2nd Floor, Ste 230 4,197 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Office/Medical Shell Space Now
2nd Floor, Ste 260 4,419 SF Negotiable Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

1st Floor, Ste 100

Size
7,028 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 120

Size
7,804 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Shell Space
Available
Now

1st Floor, Ste 130

Size
6,156 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Shell Space
Available
Now

1st Floor, Ste 140

Size
5,654 SF
Term
Negotiable
Rental Rate
$35.50 /SF/YR $2.96 /SF/MO $382.12 /m²/YR $31.84 /m²/MO $16,726 /MO $200,717 /YR
Space Use
Office
Condition
Spec Suite
Available
Now

2nd Floor, Ste 200

Size
7,538 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 230

Size
4,197 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Shell Space
Available
Now

2nd Floor, Ste 260

Size
4,419 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 100

Size 7,028 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

Direct, dedicated suite entrance with awning signage available. Newly enhanced HVAC supports specialized laboratory operations and equipment. Layout and access ideal for a surgery center.

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 18 - 57 People

1st Floor, Ste 120

Size 7,804 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Shell Space
Available Now

In shell condition with newly enhanced HVAC to support specialized laboratory operations, equipment, and plumbing.

  • Can be combined with additional space(s) for up to 13,960 SF of adjacent space

1st Floor, Ste 130

Size 6,156 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Shell Space
Available Now

In shell condition with newly enhanced HVAC to support specialized laboratory operations, equipment, and plumbing.

  • Can be combined with additional space(s) for up to 13,960 SF of adjacent space

1st Floor, Ste 140

Size 5,654 SF
Term Negotiable
Rental Rate $35.50 /SF/YR
Space Use Office
Condition Spec Suite
Available Now

Newly delivered spec lab suite with high-end finishes, offering a modern lab/office build-out and immediate occupancy.

  • Lease rate does not include utilities, property expenses or building services
  • Fits 20 - 63 People
  • Space is in Excellent Condition

2nd Floor, Ste 200

Size 7,538 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

Direct, dedicated suite entrance with awning signage available.

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 19 - 61 People

2nd Floor, Ste 230

Size 4,197 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Shell Space
Available Now

In shell condition.

2nd Floor, Ste 260

Size 4,419 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

In shell condition.

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 12 - 36 People

PROPERTY OVERVIEW

The newest life science conversion in Montgomery County, Observation Labs at 20400 Observation Drive, offers superior lab space in the heart of the Germantown life science cluster, supporting tenants in all stages of their research. This two-story, multi-stage life science building provides immediate move-in-ready options and build-to-suit opportunities, leading the way with design innovation and next-generation lab space. Phase 1 offers two remaining turnkey spec suites at 5,648 square feet and 3,847 square feet. Phase 2 is ready for tenant construction, where tenants can expand or customize their build-out. Best-in-class renovations include a new lobby, creative seating options, healthy food options in the gourmet kitchen, and shared biotech equipment, including an autoclave, a glassware washer, a deionized water system, and a flake ice machine to be shared by tenants. Critical infrastructure systems, such as a new generator and a fresh air HVAC, are in place to support life science users. Observation Labs features loading docks on each level, a 480-volt electrical supply, emergency power, and ample parking. Within minutes of the property are numerous retailers, dining options, and entertainment. With access to Interstate 270 just a quarter-mile away, Observation Labs provides an easy commute and a seamless connection to Frederick and Bethesda. Reagan Washington National, BWI, and Dulles International Airports are less than an hour away for convenient out-of-town travel. Germantown is a premier location blending urban amenities alongside picturesque suburban and natural landscapes. When research, connectivity, and convenience are key, Observation Labs is the ideal destination for your lab space.

  • Bio-Tech/ Lab Space
  • Conferencing Facility
  • Air Conditioning

PROPERTY FACTS

Building Type
Office
Year Built
2023
Building Height
2 Stories
Building Size
70,000 SF
Building Class
A
Typical Floor Size
35,000 SF
Parking
Surface Parking

LINKS

1 of 1
20400 Observation Dr, Germantown, MD - AERIAL map view
(301) 896-9090

Still interested?

Contact the brokers for more information about this property

CONTACTS

  • Mark Boyce
    Mark Boyce
  • Karla Rivera
    Karla Rivera
  • Christopher Hanna
    Christopher Hanna
  • Bill Carbaugh
    Bill Carbaugh

  • Listing ID: 36047461

  • Date on Market: 9/11/2025

  • Last Updated:

  • Address: 20400 Observation Dr, Germantown, MD 20876

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20400 Observation Dr, Germantown, MD for lease Building Photo- Image 1 of 19
Observation Labs at 20400 Observation Drive
20400 Observation Dr, Germantown, MD for lease Building Photo- Image 2 of 19
Observation Labs at 20400 Observation Drive
20400 Observation Dr, Germantown, MD for lease Building Photo- Image 3 of 19
Observation Labs at 20400 Observation Drive
20400 Observation Dr, Germantown, MD for lease Building Photo- Image 4 of 19
Outdoor Seating
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 5 of 19
Main Entrance Lobby
20400 Observation Dr, Germantown, MD for lease Lobby- Image 6 of 19
Main Entrance Lobby With Floor To Ceiling Windows
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 7 of 19
Cafe And Common Area Seating
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 8 of 19
Cafe And Common Area Seating
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 9 of 19
Cafe Coffee Machine
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 10 of 19
Water room
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 11 of 19
Water Room
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 12 of 19
Shared Equipment Including An Autoclave Room
20400 Observation Dr, Germantown, MD for lease Aerial- Image 13 of 19
Strategically Located In The Germantown Life Science Cluster Along The Interstate 270 Corridor, "DNA Alley"
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 14 of 19
Suite 100 - Multi-Stage Life Science Building Provides Immediate Move-In Ready Options
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 15 of 19
Suite 100 - Multi-Stage Life Science Building Provides Immediate Move-In Ready Options
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 16 of 19
Suite 100 - Multi-Stage Life Science Building Provides Immediate Move-In Ready Options
20400 Observation Dr, Germantown, MD for lease Interior Photo- Image 17 of 19
Suite 100 - Multi-Stage Life Science Building Provides Immediate Move-In Ready Options
20400 Observation Dr, Germantown, MD for lease Building Photo- Image 18 of 19
Observation Labs at 20400 Observation Drive
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20400 Observation Dr
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20400 Observation Dr

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Mark Boyce
(301) 896-9090

Karla Rivera
(301) 896-9016

Christopher Hanna
(240) 290-9223

Bill Carbaugh
(240) 290-9230

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